Chris Landrigan

Christopher P. Landrigan, MD, MPH is a hospitalist and patient safety researcher with a particular interest in the effects of healthcare providers' work hours, sleep deprivation, and communication on safety. Dr. Landrigan is a founding member of the Harvard Work Hours, Health, and Safety Group, as well as a member of the Center of Excellence in Patient Safety at Brigham and Women's Hospital. He helped design and conduct studies to determine rates of medication errors in pediatrics; complications and errors in the care of children with bronchiolitis; hand-off errors; and the role of computerized order entry systems in reducing errors. Over the past several years, Dr. Landrigan has been particularly focused on the relationship between resident-physician sleep deprivation and patient safety. He was lead author of an AHRQ-funded study published in the New England Journal of Medicine that found interns working traditional 24-30 hour shifts made 36% more serious medical errors, and five times as many serious diagnostic errors, as interns whose scheduled work was limited to 16 consecutive hours. He subsequently led a national cohort study published in JAMA in which interns' compliance with the ACGME duty hour standards was found to be extremely poor, suggesting the need for further efforts to implement evidence-based work hour limits. In studying the implementation of safer work hours, concerns about the safety of care handoffs have arisen. Dr. Landrigan is working to study the effects of interventions designed to improve the verbal and written handoff processes, while he continues to study implementation of evidence-based, safe work hours for physicians-in-training.


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